Journal article

A Randomized Trial of Conditioned or Unconditioned Gases for Stabilizing Preterm Infants at Birth

L McGrory, LS Owen, M Thio, JA Dawson, AR Rafferty, A Malhotra, PG Davis, COF Kamlin

Journal of Pediatrics | MOSBY-ELSEVIER | Published : 2018

Abstract

Objective: To determine whether the use of heated-humidified gases for respiratory support during the stabilization of infants <30 weeks of gestational age (GA) in the delivery room reduces rates of hypothermia on admission to the neonatal intensive care unit (NICU). Study design: A multicenter, unblinded, randomized trial was conducted in Melbourne, Australia, between February 2013 and June 2015. Infants 38°C were excluded. Primary outcome was rate of hypothermia on NICU admission (rectal temperature <36.5°C). Results: A total of 273 infants were enrolled. Fewer infants in the heated-humidified group were hypothermic on admission to NICU (36/132 [27%]) compared with controls (61/141 [43%], ..

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Grants

Awarded by National Health and Medical Research Council


Funding Acknowledgements

Supported by the Australian National Health and Medical Research Council Program (606789). J.A.D., L.S.O., M.T., and C.O.F.K. are recipients of a National Health and Medical Research Council (NHMRC) Early Career Fellowship and are supported by the Victorian Government's Operational Infrastructure Support Program. P.G.D. is the recipient of an NHMRC Practitioner Fellowship. Fisher and Paykel Healthcare (Auckland, New Zealand) supplied equipment for this study. The authors declare no conflicts of interest.